Wisconsin Discovery Portal

Researcher: Weiping Tang

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Areas of Expertise
  • Pharmaceutical industry
  • Medicinal chemistry
  • Biology
  • Drug discovery
  • Medication
  • Delivery systems
  • Pharmacology
  • Toxicology
  • Biochemistry
  • Biotechnology
  • Organic synthesis
  • Carbo- and heterocycles
  • Medicinal chemistry
  • Compounds to treat hyperlipidemia, diabetes, autoimmune diseases, cancer, and infectious diseases
  • Chemical biology
  • Biological pathways
  • Epigenetic modifications
Web Site Weiping Tang's School of Pharmacy Website
Curriculum Vitae (CV)
Issued Patent(s)
  • 8,927,280 - Compositions and methods for promoting the generation of definitive endoderm, issued January 2015.
  • 8,754,237 - Bifunctional histone deacetylase inhibitors, issued June 2014.
  • 8507274 - Compositions and methods for promoting the generation of definitive endoderm, issued August 2013.
  • 8,440,716 - Deacetylase inhibitors and uses thereof, issued May 2013.
  • 8,088,951 - Epigenetic mechanisms re-establish access to long-term memory after neuronal loss, issued January 2012.
USPTO Published Applications
  • 20160039754 - Synthesis of diindolylmethanes and indolo[3,2-B]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them, published February 2016.
  • 20150240213 - Compositions and methods for promoting the generation of definitive endoderm, published August 2015.
  • 20130331455 - Deacetylase inhibitors and uses thereof, published December 2013.
  • 20130018103 - Bifunctional histone deacetylase inhibitors, published January 2013.
  • 20120101147 - Inhibition of HDAC2 to promote memory, published April 2012.
Recent Publication(s)
  • Rhodium-Catalyzed [5+2] Cycloaddition of Inverted 3-Acyloxy-1,4-enyne and Alkyne: Experimental and Theoretical Studies. Li X, Song W, Zhao XL, Ke X, Xu X, Liu P, Houk KN, Tang W. Chemistry. 2016 Mar 15. doi: 10.1002/chem.201601195. [Epub ahead of print]

  • Synthesis of Carbazoles and Carbazole-Containing Heterocycles via Rhodium-Catalyzed Tandem Carbonylative Benzannulations. Song W, Li X, Yang K, Zhao XL, Glazier DA, Xi BM, Tang W. J Org Chem. 2016 Apr 1;81(7):2930-42. doi: 10.1021/acs.joc.6b00212. Epub 2016 Mar 21.

  • Design and synthesis of a new generation of substituted purine hydroxamate analogs as histone deacetylase inhibitors. Liu R, Wang J, Tang W, Fang H. Bioorg Med Chem. 2016 Apr 1;24(7):1446-54. doi: 10.1016/j.bmc.2016.02.005. Epub 2016 Feb 6.

  • Chiral Catalyst-Directed Dynamic Kinetic Diastereoselective Acylation of Lactols for De Novo Synthesis of Carbohydrate. Wang HY, Yang K, Yin D, Liu C, Glazier DA, Tang W. Org Lett. 2015 Nov 6;17(21):5272-5. doi: 10.1021/acs.orglett.5b02641. Epub 2015 Oct 20.
Recent Artistic Works
Collaboration
  • East China Normal University, Shanghai Engineering Research Centre of Molecular Therapeutics and New Drug Development 
  • Changzhou University, Pharmaceutical Engineering and Life Science
Research Tools
Research Facilities
E-mail Address [email protected]
Phone Number 608-890-1846
Current University UW–Madison
Department Pharmacy
Title Associate Professor
Other Appointments
Address Line 1 7125 Rennebohm Hall
Address Line 2 777 Highland Avenue
City Madison
State WI
Zip Code 53705
Bachelor's Degree B.S., Peking University, Chemistry, 1997
Master's Degree M.S., New York University, Chemistry, 1999
PhD Ph.D., Stanford University, Organic Chemistry, 2005
Other Degrees
Technologies Available for Licensing Synthesizing Natural Products to Treat High Blood Cholesterol