Wisconsin Discovery Portal

Researcher: Hasan Khatib

[ printable ]
Areas of Research Expertise
* Dairy science genetics
* Genomic imprinting in cattle
* Genes and their relation to milk production
* Identification of genes of economic importance in dairy cattle
* Sequence characteristics of imprinted genes in mammalian species
Web Site Hasan Khatib's University Web Page
Curriculum Vitae (CV)
Current/Active Funding
  • Hatch Act Formula Fund, 2008-2012, The Effects of Imprinted Genes on Maternal Behavior and Early Embryonic Lethality in Cattle
  • Wisconsin Alumni Research Foundation, 2006-2033
Issued Patent(s)
  • 7,888,021 - Methods and compositions for genetically detecting improved milk production traits in cattle, granted Feb 2011.
  •  7,807,361 - Dairy cattle breeding for improved milk production traits in cattle, granted Oct 2010.
USPTO Published Applications
  • 20100185047 - Methods and compositions for testing and breeding cattle for improved fertility and embryonic survival, July 2010.
  • 20090299130 - Methods and compositions for improved fertilization and embryonic survival, Dec 2009.
  • 20090253952 - Methods and compositions for improved fertilization and embryonic survival, Oct 2009.
  • 20090216074 - Methods and compositions for improved cattle longevity and milk production, Aug 2009.
  • 20080307535 - Dairy cattle breeding for improved mild production traits in cattle, Dec 2008.
Recent Publication(s)
  • "Association between milk protein gene variants and protein composition traits in dairy cattle"

Huang W, Lucey JA, Weigel KA, et al., Journal of Dairy Science 95(1): 440-449 Jan 2012. The objective of this study was to identify DNA markers in the 4 casein genes (CSN1S1, CSN1S2, CSN2, and CSN3) and the 2 major whey protein genes (LALBA and LGB) that show associations with milk protein profile measured by reverse-phase HPLC.

  • "Short communication: Expression and alternative splicing of POU1F1 pathway genes in preimplantation bovine embryos"

Laporta J, Driver A, Khatib H, Journal of Dairy Science 94(8): 4220-4223 Aug 2011. We hypothesized that proper gene expression level in the developing embryo is essential for embryo survival and pregnancy success.

  • "Differential expression of heat shock protein genes and their splice variants in bovine preimplantation embryos"

Zhang B, Khatib H, Driver A, et al., Journal of Dairy Science 94(8): 4174-4182 Aug 2011. As such, the objectives of this study were to profile the expression of HSP and their splice variants in bovine embryos (degenerates vs. blastocysts) and to carry out association analysis with fertility traits.

  • "Comparison of transcriptomic landscapes of bovine embryos using RNA-Seq"

Huang W, Khatib H, BMC Genomics 11 711 Dec 2010. Our study demonstrates the power of RNA-seq and provides further understanding of bovine preimplantation embryonic development at a fine scale.

Recent Artistic Works  
Collaboration
  • Intra-University Collaboration: Animal Sciences, Statistics, Horticulture, Biostatistics & Medical Informatics
  • N Carolina State University, Animal Sciences
  • NW A&F University (China), Animal Science & Technology
Research Tools  
Research Facilities  
E-mail Address [email protected]
Phone Number (608) 263-3484
Current University UW - Madison
Department Dairy Science
Title Associate Professor
Other Appointments  
Address Line 1 632 Animal Science Building
Address Line 2 1675 Observatory Drive
City Madison
State WI
Zip Code 53706
Bachelor's Degree BS, The Hebrew University of Jerusalem-Israel, Biology, 1985
Master's Degree MS, The Hebrew University of Jerusalem-Israel, Human Genetics, 1988
PhD PhD, The Hebrew University of Jerusalem-Israel, Genetics, 1995
Other Degrees
Technologies Available for Licensing