Zastrow E, Hagness SC, Van Veen BD, Physics in Medicine and Biology 55 (13): 3611-3629 Jul 2010. Non-invasive microwave hyperthermia treatment of breast cancer is investigated using three-dimensional (3D) numerical breast phantoms with anatomical and dielectric-properties realism.
Shea JD, Kosmas P, Van Veen BD, et al., Inverse Problems 26 (7): 074009 Jul 2010. The detection of early-stage tumors in the breast by microwave imaging is challenged by both the moderate endogenous dielectric contrast between healthy and malignant glandular tissues and the spatial resolution available from illumination at microwave frequencies. Differential images of the applied contrast demonstrate the potential of the approach for detecting the preferential uptake of contrast agents by malignant tissues.
Winters DW, Van Veen BD, Hagness SC, IEEE Transactions on Antennas and Propagation 58(1): 145-154 Jan 2010. The authors show that elastic net approach can produce a more acurate estimate of the distribution of dielectric properties within an anatomically realistic 3-D numerical breast phantom.
Winters DW, Van Veen BD, Hagness SC, IEEE Transactions on Medical Imaging 28 (7): 969-981 Jul 2009. Breast imaging via microwave tomography involves estimating the distribution of dielectric properties within the patient's breast on a discrete mesh. The number of unknowns in the discrete mesh can be very large for 3-D imaging, and this results in computational challenges. We propose a new approach where the discrete mesh is replaced with a relatively small number of smooth basis function.