• NIH, 2012-2015, A Mechanical Nanomembrane Detector for Time-of-Flight Mass Spectrometry
• Morgridge Institute for Research, 2012-2013, Determinants of Self-Renewal, Differentiation, and Reprogramming of hESCs
• NIH National Human Genome Research Institute, 2012-2013, Wisconsin Center for Excellence in Genomics Science

• 7,982,070 - Ionizable isotopic labeling reagents for relative quantification by mass spectrometry, granted Jul 2011.
• 7,884,324 - Nanopillar arrays for electron emission, granted Feb 2011. 
• 7,820,387 - Reactions on a solid surface, granted Oct 2010.
• 7,582,422 - Modified carbon and germanium surfaces, granted Sept 2009. 
• 7,527,928 - Reactions on a solid surface, granted May 2009.

• "To understand the whole, you must know the parts: unraveling the roles of protein-DNA interactions in genome regulation"

Smith LM, Shortreed MR, Olivier M, Analyst 136 (15): 3060-3065 Aug 2011. To be able to unravel the details of these interactions on a genome-wide basis, it is necessary to know what proteins are bound to the DNA where in the genome, and to be able to monitor how those proteins change over time and in response to external stimuli. In this brief article we outline the nature of this challenge, and propose one strategy to address it.

• "Hydroxycarboxylic Acid-Derived Organosulfates: Synthesis, Stability, and Quantification in Ambient Aerosol"

Olson CN, Galloway MM, Yu G, et al., Environmental Science & Technology 45(15): 6468-6474 Aug 2011. We present a simple method for the synthesis of quantitative analytical standards of two small hydroxycarboxylic acid-derived organosulfates, glycolic and lactic acid sulfate.

• "Quantitative proteomic analysis of the chemolithoautotrophic bacterium Nitrosomonas europaea: Comparison of growing- and energy-starved cells"

Halligan BD, Scalf M, Smith L, et al., Journal of Proteomics 74(4): 411-419 Apr 2011. The goal of these studies was to compare the composition of the N. europaea proteome in growing- and energy-starved cells using N-15 labeling and HPLC-ESI-MS/MS.

• "Parallel Detection of Intrinsic Fluorescence from Peptides and Proteins for Quantification during Mass Spectrometric Analysis"

Russell JD, Hilger RT, Coon JJ, et al., Analytical Chemistry 83(6): 2187-2193 Mar 2011. We describe here the implementation of a fluorescence detection system for measurement of the UV-excited intrinsic fluorescence (UV-IF) from peptides and proteins just prior to their exit and electrospray ionization from an ESI capillary.

• Medical College of Wisconsin, Physiology, Human and Molecular Genetics Center
• Wisconsin State Lab Hyg
• Saint Michaels College, Chemistry
• GenTel Biosciences
• GWC Technologies
• Morgridge Institute for Research
• Wisconsin Institute for Discovery

• Charge Reduction Electrospray Mass Spectrometry (CREMS)
• Piezoelectric droplet dispenser
• Inductive ion detector
• MALDI instrument