Wisconsin Discovery Portal

Researcher's Profile

Last Name

Greaser 

First Name

Marion 

Middle Initial

Areas of Research Expertise

* Structure and function of muscle proteins
* Muscle growth and protein assembly
* Postmortem changes in muscle proteins
* Developmental changes affecting cardiac titin function

Web site

Marion Greaser's University Web Page 

Curriculum Vitae (CV)

 

Current/Active Funding

  • Hatch Multi-State Research Formula Fund, 2007-2010, Molecular Mechanisms Regulating Skeletal Muscle Growth and Differentiation (NC-1131)
  • University of Wisconsin Foundation, 2004-2099, Campbell Bascom Professorship
  • Wisconsin Alumni Research Foundation, 1999-2026

Issued Patent(s)

  • 6,869,632 - Method of improving drip loss in fresh beef, pork, and poultry, granted Mar 2005.
  • 6,020,012 - Method of improving the water-holding capacity, color, and organoleptic properties of beef, pork, and poultry, granted Feb 2000.

USPTO Published Applications

Recent Publication(s)

  • "Stressing the giant: a new approach to understanding dilated cardiomyopathy"

Greaser ML, Journal of Molecular and Cellular Cardiology 47 (3): 347-349 Sep 2009. TIBIAL MUSCULAR-DYSTROPHY; MUSCLE FILAMENT TITIN; C-TERMINAL TITIN; CARDIAC-HYPERTROPHY; TARGETED DELETION; CHROMOSOME 2Q31; GENE-MUTATIONS; KINASE DOMAIN; EXPRESSION; PROTEINS

  • "GelBandFitter - A computer program for analysis of closely spaced electrophoretic and immunoblotted bands"

Mitov MI, Greaser ML, Campbell KS, Electrophoresis 30 (5): 848-851 Mar 2009. GelBandFitter is a computer program that uses non-linear regression techniques to fit mathematical functions to densitometry profiles of protein gels. Keywords: Gel Analysis; Immunoblot Analysis; Myosin; Quantitative Analysis.

  • "Acceleration of Crossbridge Kinetics by Protein Kinase A Phosphorylation of Cardiac Myosin Binding Protein C Modulates Cardiac Function"

Tong CW, Stelzer JE, Greaser ML, et al., Circ Res Sep 2008. This study showed that PKA phosphorylation of cMyBP-C accelerates crossbridge kinetics and loss of this regulation leads to cardiac dysfunction.

  • "Identifying constituents of whey protein concentrates that reduce the pink color defect in cooked ground turkey"

Sammel LM, Claus JR, Greaser ML, et al., Meat Science 77 (4): 529-539 Dec 2007. Due to the variability of whey protein concentrates and the number of constituents that do not reduce pink cooked color, the addition of calcium alone or dried milk minerals containing calcium, phosphate, and citrate, represents a better means to regularly prevent the pink color defect in cooked ground turkey.

Recent Artistic Works

 

Collaboration

  • University of Kentucky, Physiology

Research Tools

 

Research Facilities

  • Muscle Biology Laboratory

E-mail Address

mgreaser@ansci.wisc.edu 

Phone Number

(608) 262-1456 

Current University

UW - Madison 

Department

Animal Sciences 

Title

Professor 

Other Appointments

Director, Muscle Biology Laboratory

Address Line 1

274 Meat Science & Muscle Biology Laboratory 

Address Line 2

1805 Linden Drive 

City

Madison 

State

WI 

Zip Code

53706 

Bachelor's Degree

BS, Iowa State University, Animal Science, 1964

Master's Degree

MS, University of Wisconsin-Madison, Biochemistry, and Meat & Animal Science, 1967

PhD

PhD, University of Wisconsin-Madison, Biochemistry, and Meat & Animal Science, 1969

Other Degrees

 

Technologies Available for Licensing

Attachments
Created at 6/12/2007 2:07 PM  by Mindy Dawson 
Last modified at 4/23/2010 2:09 PM  by EXTWEB\alarson