Wisconsin Discovery Portal

Researcher's Profile

Last Name

Cook 

First Name

Mark 

Middle Initial

Areas of Research Expertise

* Focuses on nutritional regulation of immune function
* Tests alfalfa phytase effects in chickens
* Studies conjugated linoleic acid (CLA) effects in relation to immune function including anticarcinogenic effects and protection against muscle-wasting

Web site

Mark Cook's University Web Page 

Curriculum Vitae (CV)

Mark Cook's CV 

Current/Active Funding

  • Hatch Act Formula Fund, 2007-2010, Anti-Inflammatory Properties of Conjugated Linoleic Acid (CLA) Enriched Butter on Rodent Models of Inflammation

Issued Patent(s)

  • 7,750,117 - Methods for heat-stabilizing proteins with specific binding activities, granted July 2010. 
  • 7,579,002 - Method for improving body weight of uniformity and increasing carcass  yield in animals, granted Aug 2009.
  • 7,465,276 - Identification of disease characteristics using isotope ratios in breath, granted Dec 2008.
  • 7,166,584 - Cholesterol transport gene, granted Jan 2007.
  • 7,083,909 - Composition containing gamete or embryo and animal white yolk and the use thereof, granted Aug 2006.
  • 6,908,946 - Conjugated nonadecadienoic acid compositions, granted Jun 2005.
  • 6,562,366 - Method to prevent the formation and enhance the breakdown of bezoars in animals and humans, granted May 2003.

USPTO Published Applications

  • 20090104596 - Noninvasive measurement and identification of biomarkers in disease state, published Apr 2009.
  • 20090092639 - Immunogenic composition, published Apr 2009.
  • 20070231320 - Eggs having increased antibody titer and methods for making same, published Oct 2007.
  • 20050175602 - Methods for heat-stabilizing proteins with specific binding activities, published Aug 2005.
  • 20050154059 - Method of treating type III hypersensitive reaction-related diseases and conditions by using linoleic acid, published Jul 2005.

Recent Publication(s)

  • "IgY - Immune component of eggs as a source of passive immunity for animals and humans"

Cook ME, Trott DL, Worlds Poultry Science Journal 66 (2): 215-225 Jun 2010.  Antibodies deposited in the avian egg have been found to be a platform for the production of a diverse array of safe commercial products for improving animal health and the efficiency of their production.

  • "Structural, physiological, and stable carbon isotopic evidence that the enigmatic paleozoic fossil prototaxites formed from rolled liverwort mats"

Graham LE, Cook ME, Hanson DT, et al., American Journal of Botany 97 (2): 268-275 Feb 2010. We propose that the fossil body is largely derived from abundant, highly degradation-resistant, tubular rhizoids of marchantioid liverworts, intermixed with tubular microbial elements. Our concept explains previously puzzling fossil features and is consistent with evidence for liverworts and microbial associates in Ordovician-Devonian deposits, extensive ancient and modern marchantioid mats, and modern associations of liverworts with cyanobacteria and diverse types of fungi. Our interpretation indicates that liverworts were important components of Devonian ecosystems, that some macrofossils and microfossils previously attributed to "nematophytes" actually represent remains of ancient liverworts, and that mixotrophy and microbial associations were features of early land plants.

  • "Changes in the natural abundance of (CO2)-C-13/(CO2)-C-12 in breath due to lipopolysacchride-induced acute phase response"

Butz DE, Cook ME, Eghbalnia HR, et al., Rapid Communications in Mass Spectrometry 23(23): 3729-3725 Dec 2009.  Protein synthesis during the acute phase response probably caused the fractionation of stable isotopes observed in the plasma amino acids and in exhaled breath (CO2)-C-13 delta values.

  • "Utility of spent Single Comb White Leghorn hens for production of polyclonal egg yolk antibody"

Trott DL, Yang M, Utterback PL, et al., Journal of Applied Poultry Research 18 (4): 679-689 Dec 2009. A series of experiments were conducted to determine if spent hens could be used as a viable source of eggs for the production of egg antibodies. Experiments were designed to determine the effects of hen age and molting on egg production of an antibody to a commercially relevant soluble protein antigen (SPA).

Recent Artistic Works

 

Collaboration

  • Intra-University Collaboration: Bacteriology

Research Tools

 

Research Facilities

  • The Cook Lab

E-mail Address

mcook@wisc.edu 

Phone Number

(608) 262-7747 

Current University

UW- Madison 

Department

Animal Sciences 

Title

Professor 

Other Appointments

Director, Poultry Research Institute
Associate Editor, Poultry Science
Affiliate Faculty, Environmental Toxicology Center, Nutritional Sciences, Food Microbiology & Toxicology

Address Line 1

1064 Animal Science Building 

Address Line 2

1675 Observatory Drive 

City

Madison 

State

WI 

Zip Code

53706 

Bachelor's Degree

BS, Louisiana State University, Microbiology, 1978

Master's Degree

MS, Louisiana State University, Poultry Nutrition, 1980

PhD

PhD, Louisiana State University, Poultry Nutrition, Immunology, 1982

Other Degrees

Post doctoral, UW- Madison, Poultry Science, 1983

Technologies Available for Licensing

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Attachments
Created at 6/12/2007 2:07 PM  by Mindy Dawson 
Last modified at 8/11/2010 4:00 PM  by EXTWEB\alarson