Wisconsin Discovery Portal

Researcher's Profile

Last Name

Will 

First Name

James 

Middle Initial

Areas of Research Expertise

* Smooth muscle pharmacology
* Mechanisms which perturb homeostasis in smooth muscle including hypoxia/hyperoxia, endotoxemia, infectious disease toxins, and alterations of signal transduction pathways of any etiology
* Isolated cell, isolated tissue, and whole animal technology
* Molecular biological tools to elucidate mechanisms not testable in cell, tissue, organ, or whole animal systems

Web site

James Will's University Web Page 

Curriculum Vitae (CV)

 

Current/Active Funding

 

Issued Patent(s)

  • 4,918,061 - Method of preventing diseases caused by gram-negative endotoxin in mammals, granted Apr 1990.

USPTO Published Applications

Recent Publication(s)

  • "Taser blunt probe dart-to-heart distance causing ventricular fibrillation in pigs"

Wu JY, Sun H, O'Rourke AP, et al., IEEE Trans Biomed Eng 55 (12): 2768-2771 Dec 2008. The maximum distance between the heart and a model Taser stimulation dart, called the dart-to-heart distance, at which the Taser can directly cause ventricular fibrillation (VF), was measured in pigs. Pubmed.

  • "Taser dart-to-heart distance that causes ventricular fibrillation in pigs"

Wu JY, Sun H, O'Rourke AP, et al., IEEE Transactions on Biomedical Engineering 54 (3): 503-508 Mar 2007. To help answer the question, "Can the EMD directly cause ventricular fibrillation (VF)?" ten tests were conducted to measure the dart-to-heart distance that causes VF in anesthetized pigs [mass = 64 kg +/- 6.67 standard deviation (SD)] for the most common X26 Taser. These results suggest that the probability of a dart on the body landing in 1 cm(2) over the ventricle and causing VF is 0.000172.

  • "A floating sleeve antenna yields localized hepatic microwave ablation"

Yang DS, Bertram JM, Converse MC, et al, IEEE Transactions on Biomedical Engineering 53 (3): 533-537 Mar 2006. We report a novel coaxial antenna for hepatic microwave ablation. This device uses a floating sleeve, that is, a metal conductor electrically isolated from the outer connector of the antenna coaxial body, to achieve a highly localized specific absorption rate pattern that is independent of insertion depth.

  • "Haemostatic partial nephrectomy using bipolar radiofrequency ablation"

Pareek G, Wilkinson ER, Schutt D, et al., BJU International 96 (7): 1101-1104 Nov 2005. Results show that applying bipolar RF energy to an electrode array can enable transmural excision of renal parenchyma in vivo in a bloodless fashion without collecting system injury.

Recent Artistic Works

 

Collaboration

 

Research Tools

 

Research Facilities

 

E-mail Address

jaw@ahabs.wisc.edu 

Phone Number

(608) 262-1203 

Current University

UW- Madison 

Department

Animal Health and Biomedical Sciences / Pathobiological Sciences 

Title

Professor Emeritus 

Other Appointments

 

Address Line 1

137 Animal Health & Biomedical Sciences Building 

Address Line 2

1656 Linden Drive 

City

Madison 

State

WI 

Zip Code

53706 

Bachelor's Degree

 

Master's Degree

 

PhD

 

Other Degrees

 

Technologies Available for Licensing

Attachments
Created at 6/12/2007 2:06 PM  by Mindy Dawson 
Last modified at 6/28/2010 2:35 PM  by EXTWEB\alarson